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Department Dermatopharmacology

CALL for COOPERATION

Book Project:

Catalogue of Dermato-Pharmacological Methods

One of the aims of the Fachgruppe Deramatopharmakologie is the

collection, compilation and later on publication as a catalogue for “bookshelf and bench”

of dermato-pharmacological working methods. The spectrum shall be from molecular methods to bioengineering with respect to dermato-pharmacology. Briefly, every method which targets skin and pharmaca.
All scientists are encouraged to send us information about the methods utilized in their labaratories.
Please make use of the following spread sheet.

(1)        Description / Summary of the method

(2)        Date of acceptance into the catalog (if applicable. Version number )

(3)   Principle of the method

(4)     Scientific purpose and suggested field of application of the method

(5)     Relevance of the method

  • i.e. especially stating the need of the method regarding
  • the covered endpoints (kind and quality of the measured effects)
  • the already other established methods serving the same purpose

(6)   Protocol of the method and the corresponding standard operating procedures (SOP’s).

In which the following points must be included

  • methodological endpoints and the way they are obtained (data)
  • derivation of results from these data
  • Interpretation of the results
    If the method does not handle with experiments in humans (e.g. in vitro model or Animal trials) : Description of the suggested model for the results to be predicted in humans. 

(7)    Quality criteria : Statement of the controls

(negative controls, positive controls and if applicable, benchmark controls) and their statistical confidence intervals with which the quality of the testing procedure is confirmed.

(8) Reproducibility :

· data for reproducibility by one user
· data for comparison among different users

(9) Limitations of the method

(Note: This point is very important, as according to our experience, due to uncriticalness, developers of a new methodology often claim unlimited applicability of their methods.)

(10)    Developmental status of the method

· developed and applied only in one laboratory,
· transferred successfully to other laboratories,
· scientifically prevalidated or validated,
· if applicable: officially accepted for regulatory purposes

(11)    Critical evaluation of the method considering

· Relevance (experimental purpose, need, favouring evidence)
· reliability,
· practicability,
· effort/benefit analysis,
· relativity to other methods serving the same experimental purpose

(12)    Literature

(13)    If appropriate, reference addresses of the users of the method

(May 2000)

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